【摘要】 目的研究冬青科冬青属植物榕叶冬青Ilex ficoidea叶的化学成分。方法采用多种色谱技术进行分离纯化,通过理化性质和波谱数据进行结构鉴定。结果从榕叶冬青叶95%乙醇提取物中分离得到16个化合物,分别鉴定为无羁萜(1)、4-异无羁萜(2)、羽扇豆醇(3)、齐墩果酸(4)、3-乙酰齐墩果酸(5)、3β-乙酰-6α,13β-二羟基齐墩果烷-7-酮(6)、2-(4-羟基-苄基)-苹果酸(7)、槲皮素-3-O-α-L-阿拉伯糖苷(8)、金丝桃苷(9)、顺式丁香苷(10)、乙基-O-β-L-阿拉伯糖苷(11)、大黄酚(12)、大黄素(13)、大黄素甲醚(14)、α-菠甾醇(15)、β-谷甾醇(16)。结论所有化合物均为首次从该植物叶中分离得到,其中化合物1、2、6～8、12、13为首次从冬青属植物中分得。更多还原

【Abstract】 Objective To investigate the chemical constituents in leaves of Ilex ficoidea.Methods The various chromatographic techniques were used to isolate and purify the compounds and their structures were identified by the spectral data and physicochemical properties.Results Sixteen compounds were isolated from 95% ethanol extract and identified as friedelan-3-one(1),4-epifriedelin(2),lupeol(3),oleanolic acid(4),3-acetoxy-oleanoic acid(5),3β-acetoxy-6α,13β-dihydroxyolean-7-one(6),2-(4-hydroxybenzyl) malic acid(7),quercetin-3-O-α-L-arabinopyranoside(8),hyperoside(9),cis-syringin(10),ethyl-O-β-L-arabinopyranoside(11),emodin(12),chrysophanol(13),physcion(14),α-spinasterol(15),and β-sitosterol(16).Conclusion All the compounds are isolated from the species for the first time,among which compounds 1,2,6—8,12,and 13 are isolated from the plants in genus Ilex L.for the first time.更多还原