【摘要】 目的:了解药品不良反应(ADR)发生的特点及规律。方法:对2011年北京大学首钢医院收集的268例ADR报告进行分类、统计与分析。结果:268例ADR中,男性(139例)发生率略高于女性(129例),>60岁的患者ADR发生率较高(147例,占54.85%);静脉滴注给药较其他给药途径更易引发ADR(199例,占74.26%);抗病原微生物药引发的ADR最多(110例,占41.05%),其次是循环系统用药(41例,占15.30%);累及器官和(或)系统及临床表现以皮肤及其附件损害最为常见(137例,占51.12%)。结论:应加大ADR监测,通过ADR监测工作,了解ADR发生的特点及规律,降低ADR发生率,为临床安全用药提供参考。更多还原

【Abstract】 OBJECTIVE:To investigate the characteristics and regular patterns of adverse drug reactions(ADRs).METHODS:268 ADR cases collected in Peking University Shougang Hospital during 2011 were classified and analyzed statistically.RESULTS:The ADRs occurred more often in males than in females of the total 268 cases(139 cases vs.129 cases) and in patients aged > 60 years(147 cases,54.85%).The ADRs were mostly induced by intravenous drip infusion(199 cases,74.26%),by antimicrobial drugs(110 cases,41.05%) and drugs for circulatory system(41 cases,15.30%);the ADRs manifested mostly as damage of skin and appendants(137 cases,51.12%).CONCLUSION:ADR monitoring should be emphasized so as to familiarize the characteristics and regular patterns of ADR and reduce the incidence of ADR for clinical reference of safe medication.更多还原