【摘要】 目的:了解药品不良反应(ADR)发生的特点和一般规律,促进临床合理用药。方法:采取回顾性研究方法,对漳州市医院收集的410例ADR报告分别从患者性别、年龄、药品种类、给药途径、累及器官和(或)系统及临床表现等方面进行统计、分析。结果:410例ADR中,静脉给药引发的ADR最多,为317例,占77.3%;以皮肤及其附件的不良反应最多,为207例次,占总计698例次数的29.6%;ADR多发于60岁以上人群。结论:应重视ADR的监测和上报工作,规范临床合理用药,保证患者用药安全。更多还原

【Abstract】 OBJECTIVE:To study the characteristics and regular pattern of adverse drug reactions(ADRs) occurred in our hospital so as to promote rational clinical use of drugs.METHODS: By a retrospective study,a total of 410 ADR cases collected in Zhangzhou Hospital were analyzed in respect of patients’ sex and age,drug categories,route of administration,organs or system involved in ADR and clinical manifestation etc.RESULTS: The ADRs were mostly induced via intravenous route,accounting for 77.3%(317/410);most of the ADRs manifested as damage of skin and appendants,accounting for 29.6%(207/698);the ADRs were more often seen in patients aged above 60 years.CONCLUSION: Importance should be attached to the reporting and monitoring of ADR and standardization of clinical rational use of drugs so as to ensure patients’ medication safety.更多还原