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华泽兰清热解毒作用研究

Heat-clearing And Detoxifying Effects of Eupatorium chinense L.

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【作者】 蒋毅萍徐江平黄芳

【Author】 JIANG Yi-ping,XU Jiang-ping,HUANG Fang(Department of Pharmacology,School of Pharmaceutical Sciences,Southern Medical University,Guangzhou 510515,China)

【机构】 南方医科大学药学院药理系

【摘要】 目的研究华泽兰清热解毒作用。方法通过二甲苯致小鼠耳廓肿胀、糖皮质激素诱导小鼠免疫功能低下、干酵母致大鼠发热等实验,研究华泽兰的清热解毒作用。结果华泽兰可抑制二甲苯所致小鼠耳廓肿胀,并随剂量的增加作用增强;华泽兰能提高糖皮质激素诱导的免疫功能低下小鼠的免疫功能,且华泽兰1 g·kg-1药效作用显著;华泽兰1.5 g·kg-1能对抗干酵母所致大鼠发热。结论华泽兰具有清热解毒作用。

【Abstract】 Objective To preliminary study the antipyretic and detoxifying effect of Eupatorium chinense L.Methods The antipyretic and detoxifying effects of Eupatorium chinense L.were demonstrated through experiments on auricle swelling induced by xylene in mice,immune insufficientcy induced by glucocorticoid in mice and fever induced by dry yeast in rats.Results Eupatorium chinense L.inhibited ear swelling and the effect enhanced with the dose;Eupatorium Chinese L.improved the immune function in immunosuppressed mice and reduced the fever in rats,especially for which at the dose of 1 g·kg-1;Eupatorium Chinese L.1.5 g·kg-1 relieved fever induced by dried yeast.Conclusion Eupatorium chinense L.presents antipyretic and detoxifying function.

  • 【文献出处】 医药导报 ,Herald of Medicine , 编辑部邮箱 ,2013年05期
  • 【分类号】R285
  • 【被引频次】6
  • 【下载频次】233
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