【摘要】 目的探究药学服务计划的制定与实施对慢性阻塞性肺疾病稳定期患者的病情及生存质量的影响。方法将广州医学院附属第一医院2011年9月～2012年9月确诊为慢性阻塞性肺疾病的150稳定期患者随机分为实验组与对照组各75例,按照药学服务计划对实验组进行干预,对照组不施加任何干预措施。6个月后对两组患者的急性发作次数、肺功能情况等进行分析,并对患者生存质量使用QOL评测表进行评估。结果随访调查结果显示,干预后实验组患者急性发作次数为(1.2±0.6)次/月,较对照组的(4.4±1.3)次/月有所减少;肺功能一秒用力呼气容积(FEV1)为(1.77±0.70)L,用力肺活量(FVC)为(2.36±0.76)L,FEV1/FVC为(76.56±12.66)%,与对照组比较,差异具有统计学意义(P<0.05);通过QOL评测表进行评估,实验组患者与干预前在日常生活能力、社会活动情况、抑郁心理状态及焦虑心理状态评分相比较均较好,与对照组比较,差异亦有统计学意义(P<0.05)。结论药学服务计划可明显降低慢性阻塞性肺疾病稳定期患者急性发作次数,对肺功能情况及生存质量均有所提高。更多还原

【Abstract】 Objective To discuss pharmacy service plan’s formulation and implementation’s influences on disease analysis and quality of life of chronic obstructive pulmonary disease.Methods Divided those 150 cases of patients who had been diagnosed as chronic obstructive pulmonary disease collecting from September 2011 to September 2012 into two groups randomly and each group has 75 cases,experimental group intervened these chronic obstructive pulmonary disease patients’ medication conditions according to pharmacy service plan,and control group did not take any inter vention measures.To analyzed patients’ conditions about the number of acute attack,lung function and the quality of life(QOL) attack after six months.Results The follow-up survey results showed that the number of acute attack of ex perimental group was lower than control group [(1.2 ±0.6) vs(4.4±1.3) times every month],and the forced expiratory volume in one second(FEV1) [(1.77±0.70) L],forced vital capacity(FVC) [(2.36 ±0.76) L] and the FEV1/FVC [(26.56± 12.66)%] were improved.The evaluation of QOL showed that the improvement was remarkable in activities of daily living,social activities,the psychological state of depression and anxiety and psychological state.The differences were statistically significant between the experimental group and control group(P < 0.05).Conclusion Pharmacy service plan can significantly reduce the number of acute attack of the patients with COPD.And the lung function and the quality of life were improved.更多还原