【摘要】 目的探讨PET/CT显像在孤立性肺结节(SPN)良恶性鉴别诊断中的价值。方法本次研究收集了40例肺癌患者及20例非肺癌患者,分别在注药后1 h和2 h行PET/CT显像,分别用PET显像、PET双时相显像、CT成像对SPN的良恶性进行诊断,并计算其诊断符合率;进而用PET/CT显像及PET/CT双时相显像对SPN的良恶性进行诊断,并计算其诊断符合率;并分别对诊断符合率的差异进行统计学分析。结果 PET显像、PET双时相显像、CT成像的诊断符合率分别为74%、79%、75%,三者之间的差异无统计学意义(P>0.05);PET/CT显像、PET/CT双时相显像的诊断符合率分别为91%、91%,两者之间无差异;PET/CT显像的诊断符合率明显高于单纯PET显像及CT成像,且之间的差异有统计学意义(P<0.05)。结论双时相显像对SPN良恶性的鉴别诊断价值有限;与单纯PET显像、CT成像相比,常规PET/CT显像就能满足SPN良恶性的鉴别诊断。更多还原

【Abstract】 Objective To assess the diagnostic value of 18F-FDG PET/ CT in solitary pulmonary nodule(SPN).Methods Forty patients with lung cancer and 20 patients with benign lung lesions underwent PET,dual-phase PET,and CT 1-2 hours after injection of the radiopharmaceutical.The diagnostic accuracy was determined.Results The accuracy of PET,dual-phase PET,and CT was 74%,79%,75%,respectively(P>0.05).The accuracy was 91%for both PET/CT and dual-phase PET/CT and was significantly higher than PET or CT alone(P < 0.05).Conclusions Dual-phase PET/ CT has limited value for differentiating malignant from benign solitary pulmonary nodules.PET/CT is more accurate than PET or CT alone.更多还原