【摘要】 目的探讨声辐射力脉冲成像技术(ARFI)结合超声造影评价高聚焦超声治疗子宫肌瘤疗效的可行性。方法 38例子宫肌瘤患者(55个病灶)分别在高聚焦超声治疗前3天、治疗后6个月采用声辐射力脉冲成像检测肌瘤ARFI值,应用超声造影观察肌瘤血流灌注情况及相关参数。根据治疗后6个月超声造影情况分为完全灭活组和残存组,肌瘤内部无造影剂进入的归入完全灭活组,肌瘤内部有造影剂进入的归入残存组。结果治疗前完全灭活组和残存组的肌瘤ARFI值差异无统计学意义(P>0.05)。治疗后完全灭活组的肌瘤ARFI值高于残存组,差异有统计学意义(P<0.05)。完全灭活组的治疗后肌瘤ARFI值高于治疗前(P<0.05),残存组的治疗前和治疗后肌瘤ARFI值差异无统计学意义(P>0.05)。结论 ARFI可用于评价高聚焦超声治疗子宫肌瘤疗效,具有一定的临床意义。更多还原

【Abstract】 Objective To explore the feasibility of acoustic radiation force impulse imaging(ARFI) combined with contrast-enhanced ultrasonography(CEUS) to evaluate the curative effect of high intensity focused ultrasound(HIFU) in the hysteromyoma.Methods ARFI and CEUS were performed in 38 patients with 55 hysteromyomas.ARFI values of all lesions were measured 3 days before the HIFU treatment and 6 months after treatment.Vascular perfusion of tumors were observed by CEUS and related parameters were recorded.According to the findings of CEUS 6 after months treatment,all lesions were divided into two groups: completely inactivated group and residual group.Tumors without internal visible contrast agent were included into completely inactivated group and tumors with internal visible contrast agent were included into residual group.Results There was no significant difference in tumors′ARFI values between completely inactivated group and residual group before the treatment(P>0.05).Tumors′ ARFI values of completely inactivated group were higher than residual group after treatment,and the difference was statistically significant(P<0.05).After treatment,tumors′ARFI values became higher(P<0.05) in completed inactivated group.There was no significant difference of tumors′ARFI values after treatment in residual group(P>0.05).Conclusion ARFI can be used to evaluate the therapeutic effect of the HIFU treatment of the hysteromyoma.It has some clinical values.更多还原