【摘要】 目的探讨阿立哌唑的不良反应/事件,为临床安全用药提供参考。方法搜集两家精神疾病类杂志近几年刊登的有关阿立哌唑药品不良反应的病例报告15例,同时收集临床中不良反应病例36例,进行统计与分析。结果阿立哌唑不良反应/事件累及9大系统-器官,涉及22种表现。以肝胆系统、锥体外系统、血液系统、心血管系统较多见。88.24%的不良反应/事件在30天内发生,急性不良反应者较少。结论阿立哌唑不良反应/事件以肝胆系统、锥体外系统、血液系统、心血管系统较多,急性不良反应较少,为较理想的抗精神病药物。更多还原

【Abstract】 Objective To investigate aripiprazole adverse reactions/events,provide a reference for clinical safety of drugs.Methods We Searched two types of magazimes on mental illness in recent years,15 cases of aripiprazole adverse reaction reports were collected,together with 36 clinical cases of adverse reactions,acomprehensive statistical analysis wa conducted.Results Aripiprazole adverse reactions/events involve 9 systems-organs,including 22 manifestations.The hepatobiliary system,extrapyramidal system,blood system and cardiovascular system were more commonly involved.88.24% of the adverse reactions occurred within 30 days,acute adverse reactions were less.Conclusion Aripiprazole adverse reactions/events commonly involved the hepatobiliary system,extrapyramidal system and blood system and cardiovascular system,fewer acute adverse reactions occurred.It is an ideal antipsychotic drug.更多还原