【摘要】 目的:观察甘精胰岛素(来得时)联合阿卡波糖(拜唐萍)治疗2型糖尿病患者的临床疗效。方法:选取40例糖化血红蛋白(HbAlc)>9%的2型糖尿病患者,予每餐口服阿卡波糖,同时每晚22点睡前皮下注射甘精胰岛素治疗3个月,观察治疗前后血糖水平、低血糖发生情况及体质指数(BMI)。结果:治疗后患者的空腹血糖(FPG)、餐后2h血糖(2hPG)、HbAlc较治疗前均显著下降(P<0.05);体质指数(BMI)治疗前后无显著性差异(P>0.05);低血糖发生率为2.5%。结论:甘精胰岛素联合阿卡波糖能有效降低糖化血红蛋白(HbAlc)>9%的2型糖尿病患者的血糖,且对体重影响较小,具有安全、方便、依从性高的特点,可作为临床2型糖尿病的治疗方案。更多还原

【Abstract】 Objective:To observate the Clinical effect of glargine combined with acarbose tablets in treating newly diagnosed type 2diabetes patients.Methods:fourty newly diagnosed type 2diabetic patients(HbAlc>9%)were treated acarbose at each meal,bedtime subcutaneous injection of insulin glargine for 3months.Blood glucose level,body mess index(BMI)and incidence of hypoglycemia were observed.Results:The fasting blood glucose,post prandial two hour blood glucose,glycosylated hemoglobin were obviously decreased after treatment as compared with their pre-treatment,there was no significant difference in BMI before and after treatment.The incidence of hypoglycemia was 2.5%.Conclusion:Glargine plus acarbose can effectively reduce blood glucose of glycated hemoglobin(HbAlc)>9% newly diagnosed patients with type 2diabetes,with lower incidence of hypoglycemia and minimal effect on BMI.The ther-apeutic regimen is safe,convenient with patient compliance and can be applied to clinical therapy of type 2diabetes mellitus.更多还原