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明月草对糖尿病小鼠的降血糖作用
Hypoglycemic Effect of Angelica keiskei on Diabetic Mice
【摘要】 采用腹腔注射0.1 mL/10 g四氧嘧啶溶液建立糖尿病小鼠模型。小鼠随机分为空白对照组、模型对照组、阳性对照组、明月草低、中、高剂量组(2.5%、5.0%、10.0%),灌胃30 d,观察其对小鼠体重、血糖的影响。结果表明:明月草低、中、高剂量组的血糖值分别达到9.61±1.60、9.95±1.51、9.50±1.73 mmol/L,与模型对照组比较有显著性差异(P<0.05),说明明月草对高血糖模型小鼠有较好的降血糖功能。
【Abstract】 Mice were injected alloxan into abdominalcavity for 7 days,those which blood glucose values higher than 11.1mmol/L were animal model of diabetes.Mice were randomly divided into control group,animal model group,positive group and groups at low,medium and high doses of Angelica keiske.After being lavaged stomach for 30 days,the blood glucose values of tested mice at various doses groups are 9.61±1.60,9.95±1.51,9.50±1.73 mmol/L respectively.There are significant difference in blood glucose value compared with that of in model groups(P<0.05),which showed Angelica keiskei has good hypoglycemic effect on diabetes model mice.
【Key words】 Angelica keiskei; hypoglycemic effect; alloxan; diabetic;
- 【文献出处】 热带农业科技 ,Tropical Agricultural Science & Technology , 编辑部邮箱 ,2013年02期
- 【分类号】R285
- 【被引频次】8
- 【下载频次】356