【摘要】 目的:观察丁苯酞联合银杏达莫治疗急性脑梗死的疗效和安全性。方法:将72例急性脑梗死患者随机分为A、B、C组,在常规治疗基础上,A组给予丁苯酞软胶囊口服和银杏达莫静脉滴注,B组给予银杏达莫静脉滴注,疗程、用法相同,C组给予常规治疗,三组均治疗14d。在治疗开始前、治疗结束后分别行临床神经功能缺损评分(NIHSS)和日常生活活动能力量表(BI)评分,观察和比较各组治疗效果,并对出现的不良反应进行评估。结果:A、B、C组经治疗后NIHSS和BI评分均明显低于治疗前(P<0.05),A组治疗后NIHSS和BI评分显著低于B、C组(P<0.05)。A组治疗有效率(87.50%)明显优于B组(75.00%),差异有统计学意义(P<0.05)。结论:联合应用丁苯酞和银杏达莫对脑梗死急性发作期患者具有一定程度的协同治疗效果,而且临床应用较安全。更多还原

【Abstract】 Objective:To evaluate the clinical efficacy and safty of combined use of butylphtalide soft capsules and ginkgo leaf extract and dipyridamole injection in the treatment of acute cerebral infarction.Methods:72 cases of acute cerebral infarction were randomly divided into A,B,C groups,on the basis of routine treatment,A group was given butylphthalide soft capsules orally and ginkgo leaf extract and ginkgo leaf extract and dipyridamole injection infusion, B group was given ginkgo leaf extract and dipyridamole injection infusion,treatment,using of the same,C group was given runtine treatment,three groups were treated for 14 days.In the end before starting treatment,after treatment,clinical neural function defect score(NIHSS) and activities of daily living scale (BI) score,observed and compared the treatment effect,and to evaluate the adverse effects.Results:A,B,C groups after treatment,NIHSS and BI scores were significantly lower than that before treatment( P <0.05),after treatment in A group,NIHSS and BI were significantly lower in B and C groupss ( P <0.05).In A group, the treatment efficiency(87.50%) was significantly higher than that of B group(75.00%),there was significant difference ( P <0.05).Conclusion:The combined application of butylphthalide and ginkgo leaf extract and dipyridamole injection on acute cerebral infarction onset synergistic therapeutic effect with a certain degree of patients,but the clinical application is safe.更多还原