【摘要】 目的研究贵州省HIV感染者或艾滋病患者血液CD4+T淋巴细胞数量与HIV-1病毒载量的关系。方法每月1次采集74例HIV感染者或艾滋病患者静脉全血样本,检测CD4+T淋巴细胞及HIV-1病毒载量。结果随着HIV-1病毒载量的增加,CD4+T淋巴细胞数逐渐减少。当CD4+T淋巴细胞数>350个/μl时,1.27%的HIV-1病毒载量>105IU/ml;当HIV-1病毒载量>105IU/ml时,94.74%的CD4+T淋巴细胞数<350个/μl。结论贵州省HIV感染者或艾滋病患者血液的CD4+T淋巴细胞数量与HIV-1病毒载量的Log10值呈负相关。建议给HIV-1病毒载量>105IU/ml的患者进行抗病毒治疗。更多还原

【Abstract】 Objective To study the correlation between CD4+T cell count and HIV-1viral load in HIV infectors or AIDS cases in Guizhou province,China.Methods Blood samples were collected from 74HIV infectors or AIDS cases once per month for testing HIV-1viral load and CD4+T cell count.Results The CD4+T cell count was decreased as the HIV-1viral load increased.When the CD4+T cell count was more than 350pieces/μl,HIV-1viral load over 105IU/ml accounted for 1.27%.When the HIV-1viral load was more than 105 IU/ml,CD4+T cell count less than 350pieces/μl accounted for 94.74%.Conclusion The HIV-1viral load(Log10)and CD4+T cell count are negatively correlated in HIV infectors or AIDS cases in Guizhou province.Antiviral therapy is suitable for the patients with HIV-1viral load>105IU/ml.更多还原