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经皮冠状动脉介入治疗中局部应用肝素对慢血流及无复流的预防作用

Prevention of slow-reflow or non-reflow phenomenon by adding heparin into contrast medium during percutaneous coronary intervention in patients with acute myocardial in infarction

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【作者】 王海珠楚强贾国力

【Author】 WANG Haizhu,CHU Qiang,JIA Guoli.Department of Cardiology,Zhoukou Center Hospital,Zhoukou 466000,CHINA

【机构】 周口市中心医院心脏病科

【摘要】 目的观察急诊经皮冠状动脉介入治疗(PCI)中局部应用肝素对慢血液及无复流的预防效果。方法急诊PCI患者56例分为两组:治疗组32例,在造影剂中加入肝素;对照组24例,造影剂中不加肝素。观察术中出现慢血流及无复流现象。结果 56例均开通梗死相关血管。治疗组32例均有复流;对照组有1例无复流。治疗组慢血流发生率6.3%(2/32),明显低于对照组的33.3%(7/24)(P<0.05)。结论在造影剂中加入肝素能明显减少急诊PCI治疗中慢血流现象。

【Abstract】 Objective To observe the preventive effects of local heparin strengthening on slow-reflow or non-reflow phenomenon during the percutaneous coronary intervention(PCI) in the patients with acute myocardial in infarction(AMI).Methods Fifty-six AMI patients undergoing PCI were divided into two groups of A(32 cases,adding heparin into the contrast solution) and B(24 cases,without heparin in the contrast solution).The occurrence of slow-reflow or non-reflow phenomenon during PCI was observed and compared between two groups.Results The infarction-related vessels were opened in all 56 cases of two groups.The reflow was seen in all 32 cases of group A and non-reflow was found in one of 24 cases in group B.The occurrence rate of slow-reflow phenomenon was lower in group A than that in group B(6.3% vs.33.3%)(P<0.05).Conclusion The occurrence of slow-reflow phenomenon can be reduced significantly by adding heparin into the contrast solution during PCI in the patients with acute AMI.

  • 【文献出处】 江苏医药 ,Jiangsu Medical Journal , 编辑部邮箱 ,2013年04期
  • 【分类号】R542.22
  • 【被引频次】1
  • 【下载频次】56
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