【摘要】 目的分析辖区内儿童乙型肝炎(乙肝)表面抗原(HBsAg)携带状况,评价自1992年国家将乙肝疫苗列入计划免疫以来该疫苗在本辖区的预防接种效果。方法采用酶联免疫吸附试验法(ELISA)对1998～2011年期间来本院进行健康体检的儿童的静脉血样进行HBsAg检测。结果在检测的1 624人中,HBsAg阳性41人,阳性率为2.52%;男生813人,HBsAg阳性22人,携带率为2.71%;女生811人,HBsAg阳性19人,携带率为2.34%,两者间携带率的差异无统计学意(P>0.05)。结论乙肝疫苗免疫效果显著,应继续加强乙肝防治的相关工作,以降低乙肝在儿童人群中的感染率。更多还原

【Abstract】 Objective To analyze situation of HBsAg carrying in children,and then evaluate the effects of hepatitis B vaccine taken into country planned immunization since 1992.Methods ELISA methods were applied for HBsAg detection by using venous blood samples from children taking medical examination in the hospital in 1998 to 2011.Results In total 1 624,there were 41 HBsAg-positive youngsters,and the positive rate was 2.52%.There were 813 boys,including 22 HBsAg-positive persons,and the positive rate was 2.71%;there were 811 girls,including 19 HBsAg-positive persons,and the positive rate was 2.34%;however,the positive rate between sex groups had no statistically significance(P>0.05).Conclusion The preventions of hepatitis B vaccine are effective,and it should continue to strengthen prevention and control of hepatitis B-related works,to reduce the infection rate of HBV in children.更多还原