【摘要】 目的了解本院多重耐药鲍曼不动杆菌(MDRAB)感染患者的易感因素和对临床常用抗菌药物的耐药情况。方法收集95例MDRAB感染患者的病历资料,调查患者的临床基础状况,分析抗菌药物的应用情况,记录MDRAB药物敏感试验结果,分析MDRAB感染分布特征。结果长时间住院、入住重症监护病房(ICU)、接受机械通气和使用多种广谱抗菌药物是引起MDRAB感染的主要危险因素。结论 MDRAB是引起医院呼吸道感染的重要病原菌之一,对现有抗菌药物耐药严重,应加强抗菌药物的临床应用管理,加强病区的消毒隔离和无菌操作,预防医院感染的发生。更多还原

【Abstract】 Objective To evaluate predisposing factors of the multi-drug resistant Acinetobacter baumannii(MDRAB) infection in predisposing patients,and their resistance situation against the clinical antibacterials.Methods A total of 95 medical records of MDRAB infected patients were collected.The patients’ clinical situation were summarized,and the application of antibacterial drugs were analyzed,the MDRAB drug sensitivity test results were recorded,and the MDRAB infection distribution characteristics were analyzed.Results Prolonged hospitalization,stayed in the intensive care unit(ICU),receiving mechanical ventilation and the use of broad-spectrum antimicrobial drugs were the risk factors of MDRAB infection.Conclusion MDRAB is one of the important pathogens that cause hospital respiratory infection,and has serious resistance to the existing antimicrobial drugs.The management of clinical application of the antimicrobials and the disinfection isolation and aseptic of the wards should be strengthened,so as to prevent the hospital infection.更多还原