Aim To investigate the effect of hydrophobic fraction of Cajanus cajan(L.) Millspaugh(SDE) on bone density and blood lipid level in diabetic and obese mice.Methods The db/db congenital diabetic mice and ob/ob congenital obese mice were orally administered with SDE for 8 weeks,bone density as well as serum TG,TC,LDL-C,HDL-C,ALP and Ca2+ were measured.Results Compared to mice treated with vehicle,(1) SDE-treated db/db and ob/ob mice had greater bone density(P<0.05) and lower serum ALP level(P<0.01),with serum...