【摘要】 目的 探讨常规超声联合超声造影在乳腺癌患者腋窝淋巴结良恶性诊断中的价值。方法 对40例临床确诊乳腺癌患者的64枚肿大的腋窝淋巴结的临床资料进行回顾性分析。依据淋巴结病理检查结果将64枚淋巴结分为良性组(26枚)和转移组(38枚),均行腋窝淋巴结常规超声检查,重点观察淋巴结大小、形态、长径/短径(L/S)比值、内部回声及彩色多普勒血流显像(CDFI)。对64枚腋窝淋巴结同期进行超声造影检查,记录造影强化模式和时间。结果 与转移组相比,良性组淋巴结L/S比值明显增大(P<0.01)。2组间血流分布特点及超声造影增强模式差异有统计学意义(P<0.05),良性组多为门型血流,强化模式多为中央均匀强化;而转移组多为周围型或混合型血流,强化模式多为周围型或混合型强化。良性组超声造影强化时间明显短于转移组(P<0.01)。2组间血流阻力指数差异无统计学意义(P>0.05)。结论 常规超声联合超声造影可以显著提高对乳腺癌腋窝淋巴结良恶性的鉴别能力。更多还原

【Abstract】 Objective To study the value of conventional ultrasound combined with contrast-enhanced ultrasound imaging in the differentiation of benign and malignant lymph node in breast cancer patients.Methods Clinical data of 40breast cancer patients with 64 enlarged axillary lymph nodes were analyzed retrospectively.According to the lymph node pathological results,64 axillary lymph nodes were divided into benign(n=26) and metastatic(n=38) groups.Conventional ultrasound was used to examine the axillary lymph nodes and the size,shape,longitudinal/transverse(L/T) ratio.The inner echogenicity of the lymph nodes were evaluated and color Doppler flow imaging(CDFI) was used to detect the blood stream patterns in the lymph nodes.All the 64 axillary lymph nodes were inspected by contrast-enhanced ultrasound imaging and the contrast enhancement patterns and time were noted.Results Compared with metastatic group,the S/L ratio was significantly higher in benign group(P <0.01).Significant differences in the blood flow distribution patterns and contrast enhancement patterns were observed between the 2 groups(P <0.05).In the benign group,the main blood flow pattern was portal type and the main contrast enhancement pattern was central homogeneous enhancement,while in the metastatic group,the main blood flow patterns were peripheral or mixed types.Compared with metastatic group,the contrast enhancement time was much shorter in benign group(P <0.01).No significant difference of blood flow resistance index was observed between the 2 groups(P> 0.05).Conclusion Conventional ultrasound combined with contrast-enhanced ultrasound imaging can significantly improve the ability to identify benign and malignant axillary lymph node.更多还原