【摘要】 目的探讨辛芩雾化剂对支气管哮喘患者肺功能、EOS及IgE的影响。方法 124例支气管哮喘患者随机分为对照组(60例)和治疗组(64例)。2组均予抗炎、抗过敏、止咳、化痰等对症治疗。采用分级治疗方案,治疗组加用辛芩雾化剂雾化吸入;对照组加用必可酮气雾剂吸入,2组均于治疗2周后评估临床症状、征候积分。结果治疗组疗效与对照组比较,临床控制、显效、好转、无效4个等级及总有效率方面均无显著性差异;治疗组和对照组治疗后3个月FEV1%、PEF、PEFR值均较治疗前明显改善(P<0.05)。但2组治疗后3个月FEV1%、PEF、PEFR值比较无显著差异(P>0.05)。治疗组治疗后3个月EOS值较治疗前明显下降(P<0.05),而IgE水平在2组中治疗前后均无显著性差异(P>0.05)。结论辛芩雾化剂吸入替代激素治疗能改善支气管哮喘患者肺功能,其治疗成人支气管哮喘安全有效。更多还原

【Abstract】 Objective To explore the effects of Xin Qin alevaire on lung function,EOS and IgE levels in patients with bronchial asthma.Methods A total of 124 patients with bronchial asthma were randomly divided into treatment group(n=64) and control group(n=60).Both groups received symptomatic treatment such as anti-inflammation,anti-allergy,cough stopping,and sputum elimination.Two treatment schemes were adopted.The control group was inhaled with becotide spray and the treatment group was given Xin Qin alevaire,based on the above-mentioned symptomatic treatment.Two weeks after the treatment,the clinical efficacy of the two groups was assessed.Results There was no statistical difference between the two groups in the total effectiveness rate.Three months after the treatment,FEV1%,PEF,PEFR of both groups significantly improved(P<0.05).But no significant differences were shown between the two groups(P>0.05).Three months after treatment,EOS counts in the treatment groups dropped significantly(P<0.05).While IgE levels of the two groups showed no significant differences after treatment(P>0.05).Conclusion Xin Qin alevaire can significantly improve lung function of patients with bronchial asthma.It is safe and effective for adult patients.更多还原