【摘要】 目的:研究罗布麻泡腾片的制剂工艺。方法:采用正交设计L9(34)表安排实验,选择柠檬酸、碳酸氢钠、PEG6000、安赛密为罗布麻泡腾片辅料,采用直接压片法制备泡腾片,以泡腾片外观、硬度、崩解时限、口感为综合考察指标,优化罗布麻泡腾片的处方组成。结果:罗布麻泡腾片优化处方配比为:罗布麻干浸膏用量35%,崩解剂柠檬酸用量29%、碳酸氢钠用量29%,PEG6000用量4%、矫味剂安赛密用量3%。结论:按优化处方制备的罗布麻泡腾片崩解迅速,口感良好,制备方法简便可行。更多还原

【Abstract】 Objective: To study the preparation technology of Apocynum venetum effervescent tablets. Method: the orthogonal design L9(34)surface to arrange experiments, citric acid, sodium bicarbonate, selection, density is PEG6000 on apocynum effervescent tab lets prepared by direct compression method accessories, effervescent tablets, effervescent tablets, hardness, appearance to disintegration time, taste as the indexes, and Apocynum effervescent tablet. Results: the optimal formula of Apocynum venetum effervescent tablets for: Apocynum dry extract dosage 35%, disintegrating agent citric acid 29%, sodium bicarbonate concentration 29%, PEG6000 concentra tion 4%, flavoring agent ANN 3%. Conclusion: according to the optimized prescription preparation of Apocynum venetum effervescent disintegration rapidly, good taste, preparation method is simple and feasible.更多还原