【摘要】 目的观察体外冲击波碎石术(ESWL)联合α受体阻滞剂治疗输尿管结石并促进结石排出的有效性及安全性。方法对60例输尿管结石患者在进行ESWL后进行为期2周的临床观察,30例采用保守治疗(对照组),每天饮水2 000 mL;30例(治疗组)除采用保守治疗外,加用坦索罗辛0.4 mg,每天1次。结果 ESWL治疗后2周,两组均行影像学检查。治疗组结石排出率为76.7%(23/30),对照组结石排出率为43.3%(13/30);2周内,肾绞痛发生率治疗组6.7%(2/30),对照组16.7%(5/30),治疗组有1例出现头晕。结论α受体阻滞剂可以显著提高ESWL后结石排出率,减少肾绞痛发生率,不良反应轻微,安全、有效。更多还原

【Abstract】 Objective To observe the effectiveness and safety of extracorporeal shock wave lithotripsy(ESWL)combined with α receptor blockers in treating ureteral calculi and promoting calculous discharge.Methods 60 cases of ureteral calculi were performed the 2-week clinical observation after ESWL treatment.30 cases(control group) received the conservative treatment,2 000 mL daily drinking water;in addition to the conservative treatment,the other 30 cases(treatment group)were added with tamsulosin 0.4mg,once a day.Results The two groups all were performed the radiological examination in 2 weeks after ESWL.The stone discharge rate was 77.6%(23/30)in the treatment group and 43.3%(13/30) in the control group.The incidence rate of renal colic within 2 weeks was 6.6%(2/30) in the treatment group and 16.6%(5/30) in the control group.1 cases of dizziness was found in the treatment group.Conclusion α receptor blockers can significantly incrrease the ureteral calculous discharge rate after ESWL,reduce the incidence rate of renal colic with mild adverse reactions,which is safe and effective.更多还原