Objective To discuss the effect of mini-invasive surgery to close secundum atrial septal defects(ASD) with special occluder device.Methods Totally 109 cases with ASD were treated by occlusion via a small incision(6-36 cm) at the right anterior chest.ASD was closed with special occluder device under trans-esophageal echocardiography(TEE) guidance.Results The procedure was successfully completed in 106 cases.The mean operation time was(1.5±0.3)hours.The average intra-operative blood loss was(41.5±10.3)ml.The ...