【摘要】 目的探讨依达拉奉、巴曲酶联合治疗急性缺血性脑卒中的疗效。方法随机将180例急性脑卒中患者分为两组:对照组90例,给予阿司匹林、尼莫地平等常规药物治疗;对照组90例,在该治疗外另给予依达拉奉、巴曲酶治疗。结果治疗2周后观察组患者神经功能平均缺损评分明显少于对照组(t=17.87,P<0.01);总治疗有效率为88.9%,明显高于对照组的63.3%(57/90)(χ2=16.55,P<0.01)。观察组血浆纤维蛋白原水平治疗前后有显著差异(P<0.05)。结论给予依达拉奉、巴曲酶治疗急性缺血性脑卒中能明显改善患者神经功能并降低血浆纤维蛋白水平,表明本治疗方法有推广应用的价值。更多还原

【Abstract】 Objective To explore the effect of edaravone and batroxobin in the treatment of acute ischemic stroke. Methods 180 patients with acute ischemic stroke were divided into two groups: the control group,n = 90,were given general treatment such as aspirin,nimodipine and so on; the observation group,n =90,were given by edaravone and batroxobin additionally. Results There were significantly difference in neural function deficits 2 weeks treatment between two groups( t = 17. 87,P < 0. 01). The total effective rate in the observation group was 88. 9%,higher than that of the control group,63. 3%( 57 /90)( χ2= 16. 55,P <0. 01); and the level of plasma fibrinogen also was lower than that in the control group( P < 0. 05). Conclusion The treatment of edaravone and batroxobin on acute ischemic stroke would reduce the score of neural function deficits and the level neural function deficits,is an effective method.更多还原