【摘要】 目的探讨新疆经典型卡波氏肉瘤(Kaposi′s sarcoma,KS)患者多种样本中人类疱疹病毒8型(Hu-man Herpesvirus-8,HHV-8)的病毒感染情况。方法对8例新疆地区经典型的Kaposi肉瘤患者冰冻肉瘤、血液、尿液、唾液标本进行基因组DNA抽提,PCR法扩增HHV-8ORF26基因片段。结果 HHV-8ORF26基因检测情况和8例新疆经典型Kaposi肉瘤组织、血液、尿液和唾液中均有HHV-8感染。结论 HHV-8感染是新疆经典型KS发病的主导因素,HHV-8感染可能与KS患者多器官损害的疾病。更多还原

【Abstract】 Objective To study the Human Herpesvirus 8(Human Herpesvirus-8,HHV-8) virus infection in the Xinjiang Kaposi′s sarcoma(Kaposi′s sarcoma,KS) patients organization,body fluid,urine in.Methods Select pathological biopsy and clinical diagnosis of the patients with typical KS 8 cases from our college dermatological department outpatient and ward.Testing HHV-8 ORF26 in 8 cases of Xinjiang kaposi′s sarcoma patients′s tissue,blood,urine and saliva using ordinary PCR method,then combined with clinical to analysis.Results Xinjiang kaposi′s sarcoma patients tissue,blood,urine and saliva are in all the discovery of HHV-8.Conclusion HHV-8 virus exist in all specimen of Xinjiang typical KS patients′s tissue,blood,urine and saliva,proving once again that HHV-8 infection in Xinjiang is the typical KS′s pathogenetic leading factor,the different phase of the infection status may has some relevance with the typical KS the patient progress,and finally lead to multiple organ damage of disease.For the following research,the transmission of HHV-8 way provide relevant data support.更多还原