【摘要】 目的分析手足口病儿童病例的肠道病毒7l型(EV71)感染状况。方法采集手足口病(HFMD)病例的血样,通过ELISA间接法检测EV7lIgG和IgM抗体并分析年龄、性别分布情况。结果收集到1379例HFMD儿童病例的血样和资料,年龄为2月~13周岁,平均EV7llgG抗体阳性率为28.72%,无性别差异,平均lgM抗体阳性率为5.49%;EV71IgG阳性率随着年龄增长而呈升高趋势。EV71IgG抗体阳性率最高的年龄组为5岁组,阳性率超过50%;0~1岁年龄组的血清阳性率最低,不超过20%。结论 5岁以下低年龄儿童是肠道病毒71型的易感人群,结果可为HFMD防治提供参考依据。更多还原

【Abstract】 OBJECTIVE To analyze the Enterovirus 71 infectious status of hand-foot-mouse disease(HFMD)children.METHODS Collected the blood samples of HFDM children and tested the IgG,IgM antibody by ELISA,analyzed the age and gender distributions. RESULTS We collected 1 379 blood samples of children who were l to 13 years old.The average positive rate of EV71 IgG was 28.72%,IgM was 5.49%. The positive rate of EV71 IgG was increased by increase of age.The positive rate for EV71 IgG in the age group of 5 years old was the highest,which was﹥50%,the rate in age group 0-1 year old was the lowest,which was﹤20%. CONCLUSION Children under five are susceptible to EV71 infection. The result of this investigation could provide information to HFMD disease control.更多还原