【摘要】 目的通过研究HCV检测技术现状,评估ELISA作为最常用的HCV检测方法设置灰区的必要性。方法陈述HCV检测常规方法和确证方法的利弊,分析确证试验与ELISA检测S/CO值的相关性。结果高S/CO值标本具有较强的阳性预测值,但S/CO值靠近临界值的标本其阳性预测值无相关报道。结论设置相应合适的ELISA检测灰区,有利于在尽可能减少输血后HCV感染的前提下,较大限度地保留献血人群。更多还原

【Abstract】 OBJECTIVE To study HCV detection methods and assess the necessity of setting grey zone as the most popular method ELISA. METHODS The advantages and disadvantages of various conventional methods and confirmatory methods were stated. The correlation of confirmatory test and the ELISA S/CO values were analyzed. RESULTS Specimens with high S/CO ratio corresponded with high positive predictive value. But there was no report about positive predictive value of specimens which S/CO ratio closed to the critical value. CONCLUSION Setting appropriate gray zone of ELISA can minimize the HCV infection after blood transfusion and keep more blood donors.更多还原