【摘要】 目的观察并分析黄葵胶囊联合低分子肝素治疗儿童原发性肾病综合症的临床疗效。方法选取2010年3月～2012年3月期间某院收治的原发性肾病综合症儿童107例,随机分成2组,实验组(n=54)和对照组(n=53),实验组患儿在三联疗法上加用黄葵胶囊治疗,对照组仅采用四联疗法治疗,治疗2个月,观察记录患儿治疗前后24h尿蛋白等血清指标,观察记录患儿开始利尿和尿蛋白转阴时间。结果实验组24h蛋白尿、血清白蛋白、TC以及TG等指标的改善率(84.07%,74.24%,37.69%,53.89%)均明显高于对照组(53.57%,35.42%,21.47%,31.77%),差异有统计学意义(P﹤0.05);实验组患儿开始利尿时间和尿蛋白转阴时间(9.65±4.76,13.64±6.55)d均明显少于对照组(17.34±6.35,20.53±3.63)d,差异有统计学意义(P﹤0.05)。结论黄葵胶囊联合低分子肝素治疗儿童原发性肾病综合症的临床效果良好,起效快,症状改善明显,是值得临床大力推广应用的。更多还原

【Abstract】 OBJECTIVE To observe and analyze the clinical effect about Okra capsule combined low molecular weight heparin to treat children’s primary nephritic syndrome. METHODS Selected 107 primary nephritic syndrome children who had been accepted and treated in our hospital from March 2010 to March 2012 as study objectives. Divided them randomly into 2 groups:the experimental group (n=54) and the control group (n=53). Besides trigeminy used in the experimental group, adopted Okra capsule in treatment. As for the control group, we only adopted quadri-combination therapy as treatment. Both groups were treated for 2 months. Observed and recorded patients’ urine protein and other serum parameters before and after 14 hours of treatment. Also observed and recorded the time when patients started diuresis and the time of urine protein began to be negative.RESULTS In the experimental group, the recovery rates of 24h urine protein, serum albumin, TC and TG (84.07%,74.24%,37.69%,53.89%) were significantly higher than the control group (53.57%,35.42%,21.47%,31.77%). The time in the experimental group when patients started diuresis and the time of urine protein began to be negative (9.65±4.76,13.64±6.55) d were significantly less than the control group (17.34±6.35, 20.53 ± 3.63) d. All had the statistical significance (P﹤0.05). CONCLUSION The clinical effects about Okra capsule combined low molecular weight heparin in treating children’sprimary nephritic syndrome are favorable. It can work quickly and the improvement symptom is significantly. It is a technology that worthy to be generalized.更多还原