【摘要】 目的调查不同乙肝病毒感染状态的孕妇经被动免疫后所生婴儿乙肝病毒感染情况。方法选取某院2009年11月～2012年3月114例乙肝孕妇为研究对象,随机分成被动免疫组(52例孕妇)和未被动免疫组(62例孕妇),针对其生育婴儿的相关情况进行比较分析。结果 (1)两组婴儿出生后抗HBs抗体产生率方面比较,被动免疫组高于未被动免疫组,差异有统计学意义(P﹤0.05);两组婴儿在乙肝病毒感染率方面比较,被动免疫组低于未被动免疫组,差异有统计学意义(P﹤0.05)。(2)乙肝"大三阳"孕妇两组婴儿在出生后抗HBs抗体产生率方面比较,被动免疫组高于未被动免疫组,差异有统计学意义(P﹤0.05);两组婴儿在乙肝病毒感染率方面比较,被动免疫组低于未被动免疫组,差异有统计学意义(P﹤0.05)。结论被动免疫在阻断乙肝孕妇宫内感染率方面的临床效果较好。更多还原

【Abstract】 OBJECTIVE To investigate hepatitis B infection of babies that were born by pregnant women of different HBV infection status by passive immunization.METHODS 114 cases of pregnant women with hepatitis B in our hospital from November 2009 to March 2012 were chosen as the research object and were randomly assigned to passive immunization group(n = 52)and non-passive immunization group(n = 62).The related situations of their fertility babies were taken for comparison and analysis.RESULTS(1)Anti-HBs antibody production rate among infants after birth was higher among the passive immunization group than the non-passive immunization group,and the difference was statistically significant(P﹤0.05).Hepatitis B infection rate was lower in the passive immunization group than in non-passive immunization group,and the difference was statistically significant(P﹤0.05).(2)Anti-HBs antibody production rates among infants after birth was higher in the passive immunization group than the non passive immunization group,and there was a statistically significant difference(P﹤0.05).HBV infection among the infants was lower in the passive immunization group than the passive immunization group,and there was statistically significant difference(P﹤0.05).CONCLUSION The clinical effect of passive immunization in blocking HBV intrauterine infection rate is better.更多还原