【摘要】 目的调查评价全膝人工关节置换术(Total Knee Replacement,TKR)术后的疗效,为今后临床治疗提供相应的参考依据。方法选取全膝关节骨性关节炎及类风湿性关节炎至某院行TKR治疗的患者68例(80膝)作为研究调查对象,在术前、术后1个月分别进行膝关节HSS评分,并比较术前术后的差异,同时进行疗效评定,并分析TKR并发症发生的情况。结果术前与术后1个月随访时进行比较,HSS总分分别为40.1±10.0及77.8±12.9,评分差异具有统计学意义(P﹤0.001),术后疼痛、功能、活动度、肌力、屈曲畸形及稳定性与术前相比也有一定程度的改善,各维度评分差异也具有统计学意义(P﹤0.001)。术后疗效评定结果为:优24膝(30.0%)、良41膝(51.3%)、尚可12膝(15.0%),差3膝(3.7%),优良率为81.3%。术后1月随访时共8膝发生并发症,并发症发生率为10%,按照并发症发生例数多少排序,依次为伤口或关节内感染(40膝,50%)、下肢深静脉血栓(20膝,25%)、关节僵硬(10膝,12.5%)及腓总神经损伤(10膝,12.5%)。结论采用TKR治疗重症膝关节骨性关节炎及类风湿性关节炎可以取得较好的效果,术后各项症状和功能能够得到明显改善。更多还原

【Abstract】 OBJECTIVE To investigate the effect of TKR, and provide reference for further study. METHODS A total of 68 patients with total knee osteoarthritis were selected in our hospital. The HSS score was taken before and after surgery, and com- pared the difference of the two groups. At the same time, we compared the effect and TKR as well as complication of the two groups. RESULTS Compared the effect before and after surgery, the HSS was 40.1ared the effect before and after surgery, was a significant difference between the two groups (P﹤0.05). The pain, function, activity, myodynamia, flexion deformity and stability were improved, and all the indexes showed significant differences compared with those before surgery (P﹤0.05). The results of effect after surgery were: effective in 24 knees, better in 41 knees, good in 12 knees and bad in 3 knees. The rate of effective and better was 81.3%. After following up for 1 month, the rate of complication was 10%, and the ranks of complica- tions were infection (40 knees, 50%), DVT (20 knees, 25%), ankylosis (10 knees, 12.5%) and total nerve damage (10 knees, 12.5%). CONCLUSION TKR therapy could gain better effect for severe knee osteoarthritis and rheumatoid arthritis, and kinds of indexes and function are significantly improved.更多还原