Objective: To detect the expression levels of 14-3-3 proteins isoforms in endometriotic cysts of the ovary(ECO),and to investigate its role in the development of ECO.Methods: To analzye the mRNA expressions of all seven 14-3-3 isoforms in the ECO ectopic endometrium and normal endometrium by RT-PCR.For those differentially expressed isoforms,their protein expressions were further determined by Western blot.Results: All of the seven 14-3-3 isoforms mRNA were detected by RT-PCR both in the ECO ectopic endomet...
【基金】
江西省自然科学基金资助项目(No:010G2Y007)
【更新日期】
2013-11-01
【分类号】
R711.71
【正文快照】
子宫内膜异位症(endometriosis,EMs)是育龄期女性的常见病、多发病,3%~10%的育龄期妇女患有此病,可引起下腹痛、痛经和性交痛等,严重影响女性的健康和生活质量。卵巢是EMs最常见的发生部位,亦称卵巢子宫内膜异位囊肿(endometrioticcysts of the ovary,ECO),病变可仅累及一侧卵?