【摘要】 目的:探讨冠状动脉介入术患者对比剂肾病的发病危险因素。方法:收集我院2010年03月~2011年10月期间住院的360例接受冠状动脉介入术患者的临床资料,以血肌酐为标准,测定介入治疗前后血清肌酐,分析发生对比剂肾病危险因素。结果:360例患者发生对比剂肾病28例,发生率7.71%(28/360),Logistic回归分析发现:吸烟支年、对比剂用量、遗传、高血压病、糖尿病、干预方法有统计学意义(P<0.05),即上述因素与CIN的发病密切相关。而性别、病变支数、LDL、尿酸与CIN的发病无明显相关关系。结论:CIN的发生危险因素包括吸烟支年、对比剂用量、遗传、高血压病、糖尿病、干预方法等。更多还原

【Abstract】 Objective:Aim to investigate the risk factors of contrast- induced Nephropathy (CIN) in the percutaneous coronary inter- vention (PCI). Methods:To collect the clinical data of 360 patients who underwent the PCI from March,2010 to November,2011,In or- der to serum creatinine as a standard,recorded the creatinine (Cre) before and after treatment,and analyse the risk factors for occurrence of CIN. Results:The incidence of serum creatinine- based CIN was7. 78% (28/360) in all. Risk factors Analysis:smoking variables of years,contrast agent dosage,genetic,hypertension,diabetes,intervention methods are statistically significant. But sex,lesion count, LDL,uric acid do not show statistically significant differences. Conclusion:The occurrence of CIN is closely associated with risk factors. such as smoking,contrast agent dosage,genetic,hypertension,diabetes,intervention methods and CIN.更多还原