【摘要】 利用电感耦合等离子体-质谱仪(ICP-MS)测定板蓝根原药材和水煎液中13种元素的含量。形态研究采用高速离心和滤膜分离水煎液中的溶解态和颗粒态,元素的溶解态再用树脂XAD-4、树脂D001、树脂D301和树脂D751分别区分非极性吸附态、阳离子交换态、阴离子交换态和螯合吸附态。结果表明,板蓝根药材含有微量Cu、Pb和Cd等重金属,同时含有丰富的Mg、Ca、Fe、Al等大量元素,其中Ca含量最高,为2 739 mg.kg-1;Zn、Mg、Ca、Mn、Al和Fe的浸出率较高,在42.9%到81.9%之间;Pb和Cu的浸出率最低,只有10%左右。Zn、Mg、Ca、Mn和Pb元素颗粒态比例在0%到9.3%之间,其他元素颗粒态比例在14.3%到85.7%之间。在溶解态当中,所有元素都具有阴离子交换态;Cu、Sn、Cr和Al没有或者很少有阳离子交换态,其余元素的阳离子交换态在32.4%到98.3之间;Al、Fe、Cu、Cr和Sn没有或者很少螯合吸附态,其余元素在54.9%到98.4%之间;Zn、Cu、Sn、Cd和Pb有非极性吸附态,其余元素没有。更多还原

【Abstract】 ICP-MS was employed to determine the contents of 13 elements in both the medicinal dry roots and the decoction of Radix Isatidis.Separation of the soluble and suspension portions of these metals in the decoction was achieved by high speed centrifugation and membrane filtration.The soluble decoction was further fractionized into the non-polar adsorption species,the cation adsorption species,the anion adsorption species and the chelating adsorption species with resins XAD-4,D001,D301 and D751,respectively.The results show that medicine Radix Isatidis was rich in elements such as Mg,Ca,Fe and Al,calcium content in the roots was the highest with a concentration of 2 739 mg.kg-1.The roots also contained trace amounts of heavy metals such as Cu,Pb and Cd.For Zn,Mg,Ca,Mn,Al and Fe,their rates of releasing from the roots were relatively high,ranging from 42.9% to 81.9%.Lowest releasing rates of about 10% were observed with Pb and Cu.The suspension species of Zn,Mg,Ca,Mn and Pb were measured,ranging from 0% to 9.3% of their total amounts in the decotion.For other elements,the suspension portions made up 14.3% to 85.7% of the total.In the soluble fraction of the decoction,all elements had some anion adsorption species.Cu,Sn,Cr and Al possessed no or little cation adsorption species,while other elements displayed higher proportion of cation adsorption species,ranging from 32.4% to 98.3%.Al,Fe,Cu,Cr and Sn have no or little chelating adsorption species,but for other elements,the percentage was in the range of 54.9% to 98.4%.Apparently,only Zn,Cu,Sn,Cd and Pb tended to have some non-polar adsorption species while others elements had none of them.更多还原