【摘要】 对近12年来乳菇属真菌的化学成分及其生物活性方面的研究进行了综合分析和论述。该属真菌含有倍半萜、甾醇、含氮化合物等多种结构类型的化合物,具有明显的抗癌和抗病毒等生物活性。但目前对该属真菌活性成分和其作用机制研究还不够深入,食用乳菇的安全性也缺乏系统评价。因此,进一步明确乳菇属真菌子实体或发酵产物中的活性成分,并阐明其构效关系和作用机制,将为食用菌营养保健品的开发提供理论依据,同时也为新天然药物或农药先导化合物的发现奠定基础。更多还原

【Abstract】 Natural products and biological activities of genus Lactarius(Basidiomycetes)are outlined in this review during 2000~2012.Genus Lactarius are appreciated for chemical characteristic including sesquiterpenes,steroids,nitrogen-containing compounds and other secondary metabolites with antitumor or antiviral activities and so on.To date,however,the potential active components and especially their action mechanism are still remained unknown.And the systematic safety evaluation for these edible species is also rarely reported.Therefore,a careful chemical study of the fruiting bodies or the culture broths of genus Lactarius is necessary to realize their full potentia lapplications in human health promoting and biogenic pesticides developing.更多还原