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Chronic HBV Carrier’s Acceptance of Regular Surveilling Program in China

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【作者】 方清郝友华李磊张振华王俊忠陈明发康健杨东亮

【Author】 Qing FANG 1, 2, You-hua HAO 1, Lei LI 1, Zhen-hua ZHANG 1, Jun-zhong WANG 1, Ming-fa CHEN 1, Jian KANG 1 , Dong-liang YANG1,3 1 Devivision of Clinical Immunology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China 2 Department of Infectious Diseases, the First College of Clinical Medical Sciences, China Three Gorges University & Yichang Central People’s Hospital, Yichang 443003, China 3 Department of Infections Diseases, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China

【机构】 Devivision of Clinical Immunology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and TechnologyDepartment of Infectious Diseases, the First College of Clinical Medical Sciences, China Three Gorges UniversityYichang Central People’s HospitalDepartment of Infections Diseases, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology

【摘要】 Long-term compliance with regular surveillance is important for the prevention and timely management of chronic hepatitis B (CHB). However, there are no researches focusing on the compliance of hepatitis B virus infected patients in regular surveillance so far. The purpose of our study was to investigate the outpatient compliance with long-term regular surveillance in China. Data of 3257 CHB outpatients was pooled and analyzed to assess the outpatient’s compliance with the long-term regular surveillance plan. In all outpatients, the non-follow-up and the follow-up group accounted for 73.2% and 26.8%, respectively. Among the follow-up outpatient’s, only 48.9% received ongoing-follow-up and 51.1% were finally lost to follow-up; the median length of visiting duration was 25 months; and the predictive 1-, 2-, 3-, 4and 5-year ongoing follow-up rate was 72.7%, 52.5%, 42.4%, 33.8%, and 26.3%, respectively. In conclusion, our survey proved that the regular long-term surveillance on Chinese chronic HBV carrier is difficult to be fully implemented. A large proportion of outpatients do not receive routine follow-up and are at risk of treatment delay due to various social reasons.

【Abstract】 Long-term compliance with regular surveillance is important for the prevention and timely management of chronic hepatitis B (CHB). However, there are no researches focusing on the compliance of hepatitis B virus infected patients in regular surveillance so far. The purpose of our study was to investigate the outpatient compliance with long-term regular surveillance in China. Data of 3257 CHB outpatients was pooled and analyzed to assess the outpatient’s compliance with the long-term regular surveillance plan. In all outpatients, the non-follow-up and the follow-up group accounted for 73.2% and 26.8%, respectively. Among the follow-up outpatient’s, only 48.9% received ongoing-follow-up and 51.1% were finally lost to follow-up; the median length of visiting duration was 25 months; and the predictive 1-, 2-, 3-, 4and 5-year ongoing follow-up rate was 72.7%, 52.5%, 42.4%, 33.8%, and 26.3%, respectively. In conclusion, our survey proved that the regular long-term surveillance on Chinese chronic HBV carrier is difficult to be fully implemented. A large proportion of outpatients do not receive routine follow-up and are at risk of treatment delay due to various social reasons.

【关键词】 hepatitis B viruscompliancefollow-upoutpatient
【Key words】 hepatitis B viruscompliancefollow-upoutpatient
【基金】 supported by grants from the National Mega Research Program of China(No.2008ZX10002-011);the National Key Basic Research Program of China(No.2005CB 522901,2007CB512804,2009CB522500);the National Natural Science Foundation of China(No.30571646);Deutsche Forschungsgemeinschaft(TRR60)to Dong-liang YANG
  • 【文献出处】 Journal of Huazhong University of Science and Technology(Medical Sciences) ,华中科技大学学报(医学英德文版) , 编辑部邮箱 ,2013年02期
  • 【分类号】R446.6
  • 【被引频次】2
  • 【下载频次】24
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