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2型糖尿病患者急性心肌梗死急性期血脂特点

The characteristics of blood fat in type 2 diabetes patients in early phase of acute myocardial infarction

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【作者】 李艳艳冯津萍陈刚路雅茹寇璐李杨

【Author】 LI Yan-yan1,FENG Jin-ping2,CHEN Gang2,LU Ya-ru2,KOU Lu2,LI Yang2(1.Graduate School,Tianjin Medical University,Tianjin 300070,China;2.Department of Vasculocardiology,Tianjin Chest Hospital,Tianjin 300051,China)

【机构】 天津医科大学研究生院天津市胸科医院心内科

【摘要】 目的:分析急性心肌梗死(AMI)合并2型糖尿病患者在AMI急性期血脂水平变化特点。方法:连续入选876例因AMI住院的患者,入院后24 h内抽取空腹肘静脉血,检测血脂水平。根据患者是否合并2型糖尿病分为AMI非糖尿病组(n=557)及AMI糖尿病组(n=319),比较两组患者血脂水平差异。结果:于AMI急性期,AMI糖尿病组总胆固醇(CHO)、甘油三酯(TG)、低密度脂蛋白胆固醇(LDLC)、载脂蛋白B(apoB)均高于AMI非糖尿病组,其中CHO、TG、LDLC差异有统计学意义(P<0.05),而高密度脂蛋白胆固醇(HDLC)、载脂蛋白A(apoA)低于AMI非糖尿病组,其中HDLC差异有统计学意义(P<0.05)。结论:AMI合并2型糖尿病患者在AMI急性期血脂水平明显异常,提示应加强冠心病合并2型糖尿病患者血脂异常的防治。

【Abstract】 Objective: To analyze the characteristics of blood fat level in type 2 diabetes patients in early phase of acute myocardial infarction(AMI).Methods:The hospitalized AMI patients(n=876) were chosen and their blood fat level was detected within 24 hours after hospitalization.All patients were divided into the non-diabetic AMI group(n=557) and diabetic AMI group(n=319) according to whether the AMI patients had complicated type 2 diabetes.The level of blood fat was compared between the two groups.Results:The level of total cholesterol(CHO),triglycerides(TG),low density lipoprotein cholesterol(LDLC),apolipoprotein B(apoB) were higher in patients with type 2 diabetes than those in patients without type 2 diabetes,among which CHO,TG,LDLC differences were statistically significant(P < 0.05),the level of high-density lipoprotein cholesterol(HDLC),apolipoprotein A(apoA) were lower in patients with type 2 diabetes than those in patients without type 2 diabetes,among which HDLC difference was statistically significant(P < 0.05).Conclusion:The level of blood fat in type 2 diabetes patients in early phase of AMI are apparently unusual,It should be strengthen the prevention and control of dyslipidemia of the CHD patients who with type 2 diabetes.

  • 【文献出处】 天津医科大学学报 ,Journal of Tianjin Medical University , 编辑部邮箱 ,2013年01期
  • 【分类号】R587.1
  • 【被引频次】3
  • 【下载频次】72
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