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疏肝温肾汤治疗腹泻型肠易激综合征随机平行对照研究

Shugan Wenshen Soup Treatment of Diarrhea-Predominant Irritable Bowel Syndrome Randomized Controlled Study

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【作者】 刘战河

【Author】 LIU Zhanhe(Jiyuan City Hospital Hepatobiliary Stomach Branch,Jiyuan 459000,Henan,China)

【机构】 济源市中医院肝胆脾胃科

【摘要】 [目的]观察疏肝温肾汤治疗腹泻型肠易激综合征疗效。[方法]使用随机平行对照方法,将148例住院及门诊患者按就诊顺序编号法随机分为两组。对照组72例马来酸曲美布汀片,100mg/次,3次/d,饭前30min服用。治疗组76例疏肝温肾汤(四逆散合四神丸加味,枳壳麸炒12g,杭芍药、醋柴胡各15g,炙甘草6g,肉豆蔻、补骨脂炒各15g,五味子9g,吴茱萸3g,云苓20g,防风12g,灶心土先煎30g,黄连6g,生姜3g为引);每剂160mL×2,160mL/次,早晚饭后30min温服。连续治疗14d为1疗程。观测临床症状、复发率、不良反应。连续治疗2疗程,判定疗效。[结果]治疗组治愈64例,有效9例,无效3例,总有效率96.10%。对照组治愈31例,有效20例,无效213例,总有效率70.80%。治疗组疗效优于对照组(P<0.01)。复发率治疗组4.10%,对照组31.40%,治疗组低于对照组(P<0.01)。[结论]疏肝温肾汤治疗腹泻型肠易激综合征效果满意,服用方便,无毒副作用,值得推广。

【Abstract】 [Objective]Observe Shugan Wenshen soup treating diarrhea-predominant irritable bowel syndrome.[Methods]Using randomized controlled method,148 cases of inpatient and outpatient treatment order numbers were randomly divided into two groups.Control group,72 cases trimebutine maleate tablets,100mg / time,3 times / d,taking 30min before meals.Treatment group 76 cases of Shugan Wenshen soup(Sini san Shishenwan flavored),Zhike bran fried 12g,Hangshaoyao,Cuchaihu each 15g,Gancao Sunburn 6g,Roudoukou,Buguzhi fry each 15g,Wuweizi 9g,Wuzhuyu 3g,Yun Ling 20g,Fangfeng 12g,Zaoxintufry 30g,Huanglian 6g,Shengjiang 3g for the lead;for each agent 160mL × 2,160 mL / times,morning and evening meal 30min warm clothes.14d is a course of continuous treatment.Observation of clinical symptoms,the recurrence rate of adverse reactions.2 courses of continuous treatment,to determine efficacy.[Results] treatment group were cured 64 cases,effective in 9 cases,3 cases,the total efficiency of 96.10%.The control group were cured 31 cases,effective in 20 cases,213 cases,the total effective rate 70.80%.Treatment group than the control group(P <0.01).Relapse rate in treatment group,4.10%,31.40% in control group,the treatment group than the control group(P <0.01)[.Conclusion]Treating Liver Warming diarrhea-predominant irritable bowel syndrome satisfactory,easy to take,non-toxic side effects,worthy of promotion.

  • 【文献出处】 实用中医内科杂志 ,Journal of Practical Traditional Chinese Internal Medicine , 编辑部邮箱 ,2013年05期
  • 【分类号】R259
  • 【被引频次】3
  • 【下载频次】110
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