节点文献
参麦注射液联合西药治疗重度慢性心力衰竭随机平行对照研究
Shen Mai Injection Combined with Western Medicine Treatment of Severe ChronicHeart Failure Immediately and Controlled Study
【摘要】 [目的]观察参麦注射液联合西药治疗慢性重度心力衰竭疗效。[方法]使用随机平行对照方法,将62例住院患者按抽签法随机分为两组,对照组31例舒地尔30mg,1次/d,静滴。治疗组31例参麦注射液40mL/次,1次/d,西药治疗同对照组。连续治疗14d为1疗程。观测临床症状、血压、心率及左室射血分数、不良反应。连续治疗1疗程,判定疗效。[结果]治疗组显效20例,有效7例,无效4例,总有效率87.10%。对照组显效18例,有效3例,无效10例,总有效率67.70%。治疗组疗效优于对照组(P<0.05)。舒张压、收缩压、心率、左室射血分数指标两组均有改善,治疗组改善优于对照组(P<0.05)。[结论]参麦注射液联合西药治疗慢性重度心力衰竭疗效确切,并未增加不良反应发生率,值得推广应用。
【Abstract】 [Objective]To observe Shen Mai injection combined with western medicine treatment of chronic severe heart failure efficacy.[Methods]randomized controlled,62 inpatients balloting method were randomly divided into two groups,31 cases of Shu Er 30mg,1 times / day,intravenous infusion.Treatment group,31 cases of Shen Mai Injection 40ml / times,1 times / day,and Western medicine treatment with the control group.Continuous treatment for 14 d for a course.Observation of clinical symptoms,blood pressure,heart rate and left ventricular ejection fraction,adverse reactions.Continuous one course of treatment,to determine efficacy.[Results]treatment group,20 cases markedly effective in 7 cases,4 cases,the total efficiency of 87.10%.Control group,18 cases markedly effective in 3 cases,10 cases,the total efficiency of 67.70%.The treatment group than the control group(P < 0.05).Diastolic blood pressure,systolic blood pressure,heart rate,left ventricular ejection fraction of both groups were improved in the the improved treatment group than the control group(P < 0.05).[Conclusion]Shen Mai injection combined with western medicine in the treatment of severe chronic heart failure efficacy did not increase the incidence of adverse reactions,should be widely applied.
【Key words】 Shen Mai injection; Fasudil; Combination therapy; Chronic severe heart failure; Randomized controlled study;
- 【文献出处】 实用中医内科杂志 ,Journal of Practical Traditional Chinese Internal Medicine , 编辑部邮箱 ,2013年02期
- 【分类号】R541.6
- 【被引频次】5
- 【下载频次】57