【摘要】 目的 探讨超声引导下经皮射频消融对早期乳腺癌治疗的安全性和彻底性。方法 2例穿刺病理确诊的乳腺癌患者接受了乳腺原发病灶的射频消融治疗,消融后3个月内接受了乳腺癌根治性手术,术后进行了常规病理检查。随访12个月行影像学检查。结果 切除后病理检查显示病例一原发肿瘤长径小于2 cm(1.6 cm)的病理检查未见癌残留;病例二原发肿瘤大于2 cm(2.5 cm)的病例显示肿瘤中心区为坏死组织,范围约3.5 cm,周边见少量导管内癌成分。两例患者目前术后随访1年复查,影像学检查未见局部复发或远处转移病灶。结论 射频消融术为原发且长径小于2 cm的早期乳腺癌患者提供了一个创伤更小且更为美观的治疗选择。更多还原

【Abstract】 Objective To evaluate the effect of ultrasound guided percutaneous radiofrequent ablation treatment on breast cancer.Methods Two patients,were pathologically confirmed as breast cancer,underwent percutaneous ultrasound guided radiofrequency ablation of breast lesions,followed with radical excision of breast within 3 months after the ablation.Postoperative pathological examination was conducted.Patients were followed up for over 12 months by now.Results The postoperative pathology of case No.1,in which the original breast lesion was within 2 cm in diameter,found no tumor cells left but filled with inflammatory cells instead.Case No.2with the longer diameter as 27 mm showed majority necrotic tissues but the tissue around left with some ductal carcinoma in- situ components.One- year’s follow up found no local recurrence or distant metastasis of tumor.Condusioii Radiofrequency ablation is a promising therapy with minimally invasion and better outlooking for early breast cancer within 2 cm in diameter.更多还原