【摘要】 目的探讨不同剂量阿司匹林肠溶片治疗急性脑梗死的临床疗效。方法将87例急性脑梗死患者随机分为两组,A组44例口服100mg阿司匹林,B组43例口服300mg阿司匹林,两组均联合皮下注射5000U低分子肝素治疗。1周为1个疗程,3个疗程末观察两组患者的临床疗效和治疗前后神经功能缺损评分。结果 A组总有效率为72.7%,B组总有效率为93.0%,两组患者疗效比较,差异有统计学意义(P<0.05)。治疗前、治疗第1疗程末两组患者神经功能缺损评分比较,差异无统计学意义(P>0.05);治疗第2疗程末、第3疗程末两组患者神经功能缺损评分比较,差异有统计学意义(P<0.05)。结论口服300mg阿司匹林治疗急性脑梗死的效果明显优于口服100mg阿司匹林,且能明显改善神经功能。更多还原

【Abstract】 Objective To investigate the effects of different doses of aspirin enteric-coated tablets in the treatment of acute cerebral infarction.Methods 87 cases of acute cerebral infarction were randomly divided into two groups,44 cases in group A 100mg oral aspirin,43 cases of B group 300mg oral aspirin,two groups were combined with subcutaneous injection of low molecular heparin in treatment of 5000U.In 1 weeks for 1 courses,3 courses at the end of two groups was observed before and after treatment the clinical curative effect and nervous function defect score.Results In A group,the total effective rate was 72.7%,in B group,the total effective rate was 93.0%,therapeutic effects in the two groups,the difference was statistically significant(P<0.05).Before treatment,treatment at the end of the first course in two groups of patients with neurological deficit score comparison,the difference was not statistically significant(P>0.05);treatment at the end of the second course,at the end of the third course in two groups of patients with neurological deficit score comparison,the difference was statistically significant(P<0.05).Conclusion 300mg oral aspirin study group treatment is superior to the 100mg oral aspirin study group,curative effect is exact,marked neurological improvement.更多还原