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氨基末端-B型脑钠肽前体对心力衰竭的诊断价值
The N-terminal Pro Brain Natriuretic Peptide Diagnostic Value of Heart Failure
【摘要】 目的评价氨基末端-B型脑钠肽前体(NT-proBNP)测定对慢性心力衰竭(CHF)的诊断价值。方法选择住院患者95例,根据有无心力衰竭分为心力衰竭组和非心力衰竭组,并选择同期15例健康成人作为对照组,用电化学发光免疫法(ECLIA)分别测定3组患者血浆NT-proBNP水平。结果 3组血浆NT-proBNP水平比较,差异有统计学意义(P<0.05);两两比较,差异均有统计学意义(P<0.05)。血浆NT-proBNP水平与左室射血分数(LVEF)呈负相关(r=-0.326,P<0.05)。结论血浆NT-proBNP水平是快速诊断CHF的一个客观指标,为临床医师的诊断和治疗提供实验室依据。
【Abstract】 Objective Evaluation about the level of plasma N-terminal pro brain natriuretic peptide(NT-proBNP) diagnostic value of chronic heart failure(CHF).Methods Select 95 patients in hospital,the 95 patients were selected heart failure group and no-heart failure group,and 15 pepole of health is contrast group.We detected the level of NT-proBNP in peripheral blood sample of 95 patients with cardiac insufficiency by ECLIA.Results 3 groups of plasma NT-proBNP level,the difference was statistically significant(P<0.05);two two,the differences were statistically significant(P<0.05).The plasma level of NT-proBNP was negatively correlated with LVEF(r=-0.326,P<0.05).Conclusion NT-proBNP is an objective index,it is one of the rapid diagnosis indexes of the CHF.The provides laboratory based to clinical physicians on the diagnosis and treatment.
【Key words】 N-terminal pro brain natriuretic peptide; Heart failure; Left ventricular ejection fraction; Diagnosis;
- 【文献出处】 实用心脑肺血管病杂志 ,Practical Journal of Cardiac Cerebral Pneumal and Vascular Disease , 编辑部邮箱 ,2013年01期
- 【分类号】R541.61
- 【被引频次】8
- 【下载频次】110