【摘要】 目的探讨人体呼吸频率调节下血压即时变异(blood pressure instant variability,BPIV)与心率变异(HRV)的关系。方法将52名健康受试者随机分为两组,分别在改变呼吸频率5-10-15次/min(A组,n=25)和8-12-16次/min(B组,n=27)的条件下,同步记录心电,血压和呼吸,并进行分析。结果在10-15次/min和8-12-16次/min不同频率的呼吸调节下,R-R变化趋势、血压-血压变化趋势和呼吸波变化趋势完全同步。呼吸频率/心搏频率与呼吸峰中心频率(RSP)、BPIV、HRV的中心频率的相关系数分别为0.924、0.902、0.913。在5次/min频率的呼吸调节下,R-R变化趋势、血压-血压变化趋势和呼吸波变化趋势出现了不同步现象。结论在一定呼吸频率调节下,BPIV符合呼吸性窦性心律不齐的生理机制,也符合呼吸性窦性心律不齐形成的心率变异机制,是RR间期变化的二次效应。但当呼吸频率过低的情况下,BPIV不符合呼吸性窦性心律不齐形成的心率变异机制。更多还原

【Abstract】 Objective To discuss the relationship between blood pressure instant variability(BPIV) and heart rate variability(HRV) of human under respiratory control. Methods Fifty-two healthy people′s ECG, blood pressure (BP)and respiration were synchronously recorded and analyzed when respiratory rate were controlled at 5-10-15 times/min and 8-12-16 times/min. Results At respiratory rate of 10-15 times/min and 8-12-16 times/min, R-R variation trend and BP-BP variation trend were fully synchronized with respiratory wave variation trend. Correlation coefficients(r) of center frequency of RF/HR with peak of respiratory(RSP), BPIV and HRV were 0.924, 0.902 and 0.913, respectively. At respiratory rate of 5 times/min, R-R variation trend and BP-BP variation trend were desynchronized. Conclusions At certain respiratory rate, BPIV is corresponded with the physiological mechanism of respiratory sinus arrhythmia and HRV mechanism caused by respiratory sinus arrhythmia. However, BPIV is not corresponded with the physiological mechanism of HRV mechanism caused by respiratory sinus arrhythmia when respiratory rate is too low.更多还原