【摘要】 目的通过在线尿素清除率监测法(DIASCAN)研究单次透析过程中,随着时间的推移,尿素清除率K有无变化,透析的时间对尿素清除率K有无影响。方法随机选择病情稳定且血管通路功能良好的慢性肾衰竭(尿毒症期)维持性血液透析的患者30例,在其每一次透析过程始终,保持透析设备的各种参数不变,并且维持患者的血流量稳定且保持相同,血流量设定为250 ml/min,利用瑞典金宝GAMBRO公司AK96血液透析机随机自带的在线尿素清除率监测法DIASCAN,连续观察记录每一次透析全过程中的K值结果,时间间隔设置为30 min,除去各种突发因素如设备或患者自身因素导致血流量不稳定时所观察到的K值,分析透析时间对K值的影响。结果在一次透析过程中,单次透析时间与尿素清除率K不相关(P>0.05)。结论在一次透析的全过程中,透析效率不受时间影响,增加透析时间可以提高透析充分性。更多还原

【Abstract】 Objective At present dialysis machines provided online assessment of Kt/V.The aim of our study was to assess the effect of hemodialysis time on the rate of urea removal(K),by measuring K at different times of hemodialysis patients.Methods The K during one hemodialysis session were observed chronologically.The relationship between hemodialysis time and K were analyzed.Results There was no correlation between the hemodialysis time and K(P > 0.05).Conclusion The rate of urea removal was uncorrelated with hemodialysis time during one hemodialysis session.Kt / V was positively correlated with hemodialysis time.更多还原