【摘要】 目的:了解右美托咪啶对正颌手术全麻苏醒期的影响。方法:40例ASA I-II级择期行颌面外科正颌手术患者,随机分为右美托咪啶组(D组)和生理盐水组(C组)。D组患者术毕前30 min给予右美托咪啶0.6μg/kg,泵注10 min后以0.4μg(kg.h)持续泵入。C组患者以相同速率输注生理盐水。在患者清醒(T1),拔管(T2),拔管后20 min(T3)行Ramsay评分;在T2记录2组躁动率;在T3行全麻后舒适度(BCS)评分。结果:与C组相比,D组在T1、T2、T3的Ramsay评分明显增加(P<0.05);2组在T2躁动率有明显差异(P<0.05);D组BCS评分明显高于C组(P<0.05)。结论:术毕前泵入右美托咪啶可明显减少正颌手术患者拔管期躁动程度,并且提高患者带管耐受性。更多还原

【Abstract】 Objective:To study the effect of dexmedetomidine on the recovery of patients after general anesthesia in orthognathic surgery.Methods: 40 patients with ASA I-II degree jaw deformity undergoing orthognathic surgery were randomly divided into dexmedetomidine group(D) and normal saline group(C) with 20 cases in each.In group D,dexmedetomidine was administered intravenously at 0.4 μg(kg·h) after a bolus infusion at 0.6 μg/kg for 10 min before ending operation.Normal saline was given by the same way in group C.Ramsay sedation scores were monitored at the time of awaken(T1),immediately after extubation(T2),20 min after extubation(T3);the restlessness assessment was recorded at T2 and the bruggrmann comfort scale(BCS) assessment was recorded at T3.Results: Ramsay sedation scores were higher at T1,T2 and T3 in group D than those in group C(P<0.05);the restlessness in group D was less than in group C at T2(P<0.05);the BCS was significantly higher in group D than in group C.Conclusion: Dexmedetomidine given before ending operation may decrease the restlessness in patients undergoing orthognathic surgery and improve the tolerance of retaining tracheal catheter.更多还原