【摘要】 目的 对山西省出生缺陷监测的先天性心脏病(CHD)进行流行病学分析,了解围生期CHD的变化趋势和影响因素。方法 监测2008~2012年全省42所县级及以上的医院住院分娩的孕满28周至生后7 d的围生儿。结果 2008~2012年山西省围生期CHD发生率出现上升趋势,城市上升趋势明显,农村变化趋势不明显;CHD发生率无性别差异;除2012年外,其他年度无明显城乡差异;围生期CHD的产前诊断比例逐年增高。结论 山西省监测到的围生期CHD发生率受到孕期保健、产前诊断和生后早期诊断水平的影响。更多还原

【Abstract】 Objective To describe the epidemiological characteristics of congenital hearth defects(CHD) during the perinatal period in Shanxi Province and to investigate the time trend.Methods The surveillance program consisted of 42 hospitals in Shanxi Province.We collected information about CHD during the perinatal period from 2008 to 2012. Subjects included fetuses of 28 completed weeks of gestation or greater(including live-birth and stillbirth) and newborn of 7 completed days after birth or smaller.Results From 2008 to 2012,the overall CHD prevalence increased from 6.5 per 10,000 to 12.0 per 10,000.In urban area,the prevalence of CHD was 6.3 per 10,000 and 15.9 per 10,000 in 2008 and 2012,respectively,indicating an increasing trend.In rural area,the prevalence of CHD was 6.3 per 10,000 and 9.0 per 10,000 in 2008 and 2012,respectively,with no apparent increasing trend.The proportion of CHD diagnosed before birth increased year by year.Conclusion The prevalence of CHD increased during the 5 years of surveillance.This increasing trend may be affected by early detection and diagnosis.更多还原