【摘要】 目的 从影像学角度探讨高海拔地区肺间质性疾病合并肺纤维化(PF-ILD)的高分辨率CT(HRCT)特征及其与病因、病程的关系。方法 对94例高海拔地区肺间质疾病中77例合并PF-ILD患者的HRCT特征、临床资料进行回顾性分析。结果 高海拔地区肺间质疾病的HRCT表现为:小叶间隔增厚59例(76.6%),小叶内间质增厚48例(62.3%),支气管血管束异常31例(40.3%),胸膜下弧线影29例(37.7%),磨玻璃密度影20例(26.0%),蜂窝征42例(54.5%),网格状35例(45.5%),支气管扩张29例(37.7%),多发结节影6例(7.8%),肺气肿56例(72.7%),肺大泡22例(28.6%)。结论 高海拔地区PF-ILD发病率明显偏高(约81.9%),病程长,合并症多,与高海拔缺氧及慢性高原疾病关系密切,HRCT检查具有重要的临床应用价值。更多还原

【Abstract】 Objective To explore the high-resolution CT(HRCT) characteristics of interstitial lung disease with pulmonary fibrosis(PF-ILD) in high altitude region,and the relationship among the image character,etiology and course of the disease.Methods HRCT features and clinical data of 77 patients who were detected PF-ILD were retrospectively analyzed.Results HRCT characteristics of ILD in high altitude areas were as follows:interlobular septal thickening in 59 cases(76.6%),lobular septal thickening in 48patients(62.3 %),abnormality of bronchovascular bundles in 31 cases(40.3%),subpleural line in 29 cases(37.7%),ground-glass opacity in 20 cases(26.0%),Honeycomb sign in 42 cases(54.5%),reticular opacities in 35 cases(45.5%),bronchiectasis in 29cases(37.7%),multiple nodules in 6 patients(7.8%),emphysema in 56 cases(72.7%),bullae in 22 cases(28.6%).Conclusion The PF-ILD morbidity in high altitude was relatively high(about 81.9%),with long course and many complications,which may be closely related with high altitude hypoxia and chronic plateau diseases.HRCT play an important role in clinics of PF-ILD.更多还原