【摘要】 目的:研究单纯性肥胖患儿BMI相关危险因素,为预防肥胖相关疾病在儿童中的流行提供一定的指导。方法:对68例单纯性肥胖儿童测量身高、体重,留空腹血并检测血脂、肝功、血糖、胰岛素、C反应蛋白、单核细胞趋化因子、内脂素。结果:线性相关分析显示,BMI与C反应蛋白、单核细胞趋化因子、谷草转氨酶、甘油三酯、总胆固醇、高密度脂蛋白、低密度脂蛋白、胰岛素等具有简单线性相关;多元线性回归显示,甘油三酯、胰岛素、C反应蛋白、低密度脂蛋白与BMI密切相关。结论:甘油三酯、胰岛素、C反应蛋白、低密度脂蛋白与肥胖相关疾病密切相关,肥胖儿童通过降低其BMI水平,对于预防血脂紊乱、炎症性疾病及2型糖尿病的发生有重要意义。更多还原

【Abstract】 Objective:To study the relation between BMI and risk factors of obesity-related disease and provide some guidance for preventing of obesity-related disease prevalence in children.Method:We recruited 68obese children and the subjects’ body weight,height were measured according to standardized techniques.Also lipids,liver function,blood glucose,insulin,C-reactive protein,monocyte chemotactic factor,visfatin were tested.Results:The linear correlation analysis showed that BMI had a simple linear correlation with C-reactive protein,monocyte chemotactic factor,aspartate aminotransferase,triglycerides,total cholesterol,high density lipoprotein,LDL and insulin,we analysis with multivariate linear regression and it showed that triglycerides,insulin,C-reactive protein,low-density lipoprotein were closely related with BMI.Conclusion:Triglycerides,insulin,C-reactive protein and low-density lipoprotein are closely related to obesity-related diseases.It is important for obese children reduce the level of BMI to prevent lipid disorders,inflammatory diseases and type 2diabetes.更多还原