【摘要】 目的:探讨分娩镇痛对产妇胰岛素抵抗的影响。方法:将60例初产妇随机分为分娩镇痛组(A组)和对照组(C组),每组30例。A组分娩时采用连续硬膜外镇痛;C组分娩时不施行镇痛,各组于出现规律宫缩时(T1)、宫口开全时(T2)、胎儿娩出时(T3)、胎盘娩出后30min(T4)测空腹血糖(FPG)、空腹胰岛素(FINS),并计算胰岛素抵抗指数[ln(HOMA-IR)]。结果:在T2和T3时点,A组FPG、FINS及ln(HOMA-IR)的值均低于C组(P?0.05);在T1和T4时点,C组与A组的FPG、FINS及ln(HOMA-IR)值无显著性差异(P>0.05)。结论:分娩镇痛可减轻胰岛素抵抗程度和血糖升高程度,提高分娩期母婴安全。更多还原

【Abstract】 Objective:To investigate the influence of labor analgesia on insulin resistance in puerpera.Methods:60 healthy primiparae were randomly divided into 2 groups(n=30 each):control group(group C,labor without analgesia),labor analgesia group(group A).Fasting plasma glucose(FPG) and fasting insulin(FINS) were examined at the time points of regular uterine contraction(T1),complete dilatation of cervix(T2),fetal disengagement(T3) and placental expulsion(T4),then calculated the homeostasis model assessment of insulin resistance[ln(HOMA-IR)].Results:FPG,FINS and ln(HOMA-IR) in group A were all lower than in group C at the time points of T2 and T3(P<0.05).There was no significant difference between group C and A in FPG,FINS and ln(HOMA-IR) at the time points of T1 and T4(P>0.05).Conclusion:Labor analgesia can relieve insulin resistance in puerpera.更多还原