Objective To observe the curative effect of plague bacteriophage on Yersinia pestis infection in mice and in-vestigate a novel therapeutic method for plaque.Methods Mouse model of plaque infection was established by subcuta-neous infection with Y.pestis 141 strain.Model mice were treated with 100 μl of plaque bacteriophage at a titer of 10-11 3,6,12 and 24 h after infection to observe the short-term curative effect,or with 100 μl of plaque bacteriophage once a day 1~7 d after infection to observe the long-t...
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