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低强度脉冲超声波对聚四氟乙烯膜和Bio-Gide胶原膜超声通透性研究

Research on Ultrasonic Permeability of Low Intensity Pulsed Ultrasound through PTFE Membrane and Bio-Gide Collagen Membrane

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【作者】 柴召午赵纯亮宋锦璘邓锋杨霁高翔刘珉懿

【Author】 Chai Zhaowu;Zhao Chunliang;Song Jinlin;Deng Feng;Yang Ji;Gao Xiang;Liu Minyi;The Affiliated Hospital of Stomatology,Chongqing Medical University,Chongqing Key Laboratory of Oral Diseases and Biomedical Science;Chongqing Key Laboratory of Ultrasound Medical Engineering Cofounded by Chongqing and Ministry of Science andTechnology;Department of Stomatology,Tongliang County People’s Hospital of Chongqing;

【机构】 重庆医科大学附属口腔医院,口腔疾病与生物医学重庆市重点实验室重庆市超声医学工程重点实验室省部共建国家重点实验室培育基地重庆市铜梁县人民医院口腔科

【摘要】 检测低强度脉冲超声波(LIPUS)对0.01mm厚度聚四氟乙烯(PTFE)膜和Bio-Gide胶原膜超声透过率,为LIPUS辅助引导组织再生(GTR)术实验研究提供屏障膜的遴选依据。设定LIPUS频率1.5MHz,脉宽200μs,重复率1.0kHz,功率为10~100mW/cm2,间隔10mW/cm2设一检测值,共10组,分别对两种屏障膜的超声透过率进行检测。发现0.01mm厚度PTFE膜超声透过率为78.1%~92.3%,Bio-Gide胶原膜超声通过率为43.9%~55.8%。0.01mm厚度PTFE膜超声透过率明显高于Bio-Gide胶原膜,不同功率下同一屏障膜的超声透过率有统计学差异(P<0.05)。结果表明,0.01mm厚度PTFE膜和Bio-Gide胶原膜超声透过率均较高,应依据不同实验需求遴选屏障膜,并进行超声透过率实验以确保有效功率。

【Abstract】 The aim of the present study was to detect the transmission rate of ultrasonic low intensity pulsed ultrasound(LIPUS)through polytetrafluoroethylene(PTFE)membrane(Thickness:0.01mm)and Bio-Gide collagen membrane,and to provide the basis for the barrier membrane selection on the study of LIPUS combined with guided tissue regeneration(GTR).The ultrasonic(LIPUS,frequency 1.5MHz,pulse width 200μs,repetition rate 1.0kHz)transmission coefficient of the two kinds of barrier membrane were detected respectively through setting ten groups from 10to 100mW/cm2 every other 10mW/cm2.We found in the study that the ultrasonic transmission coefficient through 0.01mm PTFE membrane was 78.1%to 92.3%,and the ultrasonic transmission coefficient through Bio-Gide collagen membrane was 43.9%to 55.8%.The ultrasonic transmission coefficient through PTFE membrane was obviously higher than that through Bio-Gide collagen membrane.The transmission coefficient of the same barrier membrane of the ultrasonic ion was statistically different under different powers(P<0.05).The results showed that the ultrasonic transmittance rates through both the 0.01mm PTFE membrane and Bio-Gide collagen membrane were relatively high.We should select barrier membranes based on different experimental needs,and exercise ultrasonic transmission coefficient experiments to ensure effective power.

【基金】 国家自然科学基金资助项目(30870754);重庆市发展和改革委员会高技术产业重大产业技术开发基金资助项目[渝发改技(2007)1110号];重庆市科委自然科学基金资助项目(CSTC2010BB-5355);重庆市卫生局资助项目(2010-2-232)
  • 【文献出处】 生物医学工程学杂志 ,Journal of Biomedical Engineering , 编辑部邮箱 ,2013年06期
  • 【分类号】R781.4
  • 【下载频次】149
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