【摘要】 目的:探讨主动脉内球囊反搏术(IABP)在不同类型急性心肌梗死患者中的有效性及对预后的影响。方法:入选2010年1月至2011年06月应用IABP治疗的急性心肌梗死患者62例,分为两组:A组为ST段抬高组,共34人;B组为非ST段抬高组,共28人。收集并观察两组的即刻病情改善率、术后30天、3月的左室射血分数(LVEF)及室壁运动积分指数(WMSI)、主要心血管事件(MACE)发生率。结果:B组IABP即刻有效性显著优于A组(10/25比8/30,P<0.05)。术后30天,A、B两组LVEF均较术前增加,且组间具有统计学差异(35.5%±5.2%比40.6%±4.9%,P<0.05);在MACE事件上,A组仅在死亡例数一项明显高于B组(10/30比6/25,P<0.05)。术后3月,A、B两组LVEF、WMSI有统计学差异(37.0%±6.9%比44.2%±5.2%;1.7±0.4比1.3±0.5,P均<0.05)。A组MACE事件发生率明显高于B组,主要表现在非致死性心肌梗死和死亡两方面(3/30比1/25;15/30比8/25,P均<0.01)。结论:IABP对于不同类型急性心肌梗死疗效存在差异,非ST段抬高心肌梗死疗效尤为显著。更多还原

【Abstract】 Objective: To evaluate the effect of intra-aortic balloon pump(IABP) in patients with acute myocardial infarction.Methods: A total of 62 patients with acute myocardial infarction(AMI) were selected in this study,treated with IABP between January 2010 and June 2011,divided into ST-segment elevation(group A,n=34) and non-ST-segment elevation(group B,n=28).Some indicators and indices were collected and observed between the two groups,including immediate therapeutic efficacy(ITE),left ventricular ejection fraction(LVEF) and wall motion score index(WMSI) as well as major adverse cardiac events(MACE) at 30 days and at 3 months after operation.Results: Group B was superior to group A in ITE(10/25 vs.8/30,P<0.05).After 30 days LVEF was obviously improved in the two groups,with significant difference(35.5%±5.2% vs.40.6%±4.9%,P<0.05).Mortality rate of group A was higher than that of group B(10/30 vs 6/25,P<0.05).Three months after operation,there were significant differences in LVEF and WMSI between the two groups.MACE event rate of group A was significantly higher than that in group B,mainly in the non-fatal myocardial infarction and mortality rate(3/30 vs.1/25;15/30 vs.8/25,P all<0.01).Conclusions: There are differences in the effects of IABP on different types of acute myocardial infarction,and the efficacy for non-ST-segment elevation patients with myocardial infarction is particularly significant.更多还原