【摘要】 目的:探讨开腹子宫切除术术式对阴道免疫防御功能的影响,为临床恰当选择经腹子宫切除术术式提供参考。方法:经腹子宫切除术99例分为研究组(37例,次全子宫切除术)和对照组(62例,全子宫切除术),检测其术前及术后1个月阴道分泌物中免疫因子(SIgA、IL-2、-10)含量及病原微生物。结果:两组术后阴道分泌物中免疫因子含量明显下降(P<0.01),对照组下降更明显(P<0.05)。两组术后外阴阴道假丝酵母菌检出率分别为12.1%和39.6%,细菌性阴道病3.0%和18.8%。研究组阴道炎症发生比例明显低于对照组(P<0.05)。结论:经腹全子宫切除术后患者阴道免疫防御功能易受损而发生阴道炎症。更多还原

【Abstract】 Objective:To investigate the effect of abdominal hysterectomy on function of immune defense of the vagina,and to find appropriate choice of abdominal hysterectomy.Methods:Ninety-nine patients who accepted abdominal hysterectomy were divided into study group(37 cases,accepted abdominal subtotal hysterectomy)and control group(62 cases,accepted abdominal total hysterectomy).The concentrations of immune factors(SIgA,IL-2,-10) and pathogens were assayed before operation and one month after operation.Results:The concentrations of immune factors in vaginal discharge decreased significantly between two groups after operation(P<0.01),the decrease in the control group was obvious(P<0.05).The ratio of Vulvovaginal candidiasis between two groups after operation was 12.1% and 39.6%,3.0% and 18.8% of bacterial vaginosis respectively.The vaginitis in the study group was less than that in the control group(P<0.05).Conclusion:The patients accepted abdominal total hysterectomy is easily impaired in the function of immune defenses of the vagina,but suffering from vaginitis.更多还原